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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-7
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pubmed:abstractText |
Intrauterine growth restriction (IUGR) is characterized by decreased placental perfusion. Low oxygen has been shown to increase soluble fms-like tyrosine kinase 1 (sFlt-1) expression in the human placenta. The objective of this study was to examine sFlt-1 expression in different types of IUGR pregnancies, including early-onset severe cases characterized by abnormal umbilical and uterine artery Doppler and discordant IUGR twins in which the normal cotwin represents the optimal control because both placentas share the same uterine environment.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-972X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
285-92
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17956955-Adult,
pubmed-meshheading:17956955-Blotting, Western,
pubmed-meshheading:17956955-Female,
pubmed-meshheading:17956955-Fetal Growth Retardation,
pubmed-meshheading:17956955-Humans,
pubmed-meshheading:17956955-Immunohistochemistry,
pubmed-meshheading:17956955-Infant, Newborn,
pubmed-meshheading:17956955-Infant, Small for Gestational Age,
pubmed-meshheading:17956955-Placenta,
pubmed-meshheading:17956955-Pre-Eclampsia,
pubmed-meshheading:17956955-Pregnancy,
pubmed-meshheading:17956955-Pregnancy, Multiple,
pubmed-meshheading:17956955-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17956955-Twins,
pubmed-meshheading:17956955-Ultrasonography, Doppler,
pubmed-meshheading:17956955-Umbilical Arteries,
pubmed-meshheading:17956955-Vascular Endothelial Growth Factor Receptor-1
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pubmed:year |
2008
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pubmed:articleTitle |
Placental expression of soluble fms-like tyrosine kinase 1 is increased in singletons and twin pregnancies with intrauterine growth restriction.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, Mount Sinai Hospital, 600 University Avenue, Room 871C, Toronto, Ontario, Canada M5G 1X5.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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