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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-1-22
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pubmed:abstractText |
Tardive dyskinesia is a syndrome of abnormal and involuntary movements which occurs as a complication of long-term neuroleptic therapy especially classical neuroleptics such as haloperidol and chlorpromazine. Dysfunction of GABA receptor mediated inhibition, and increased glutamatergic neurotransmission has been implicated in the development of orofacial dyskinesia in rats and tardive dyskinesia in humans. Neurosteroids modulate both GABAergic as well as glutamatergic neurotransmission in various brain areas.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Catalase,
http://linkedlifedata.com/resource/pubmed/chemical/Dehydroepiandrosterone Sulfate,
http://linkedlifedata.com/resource/pubmed/chemical/Haloperidol,
http://linkedlifedata.com/resource/pubmed/chemical/Homovanillic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Pregnanolone,
http://linkedlifedata.com/resource/pubmed/chemical/Pregnenolone,
http://linkedlifedata.com/resource/pubmed/chemical/Progesterone,
http://linkedlifedata.com/resource/pubmed/chemical/Serotonin,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxide Dismutase,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0033-3158
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
196
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
243-54
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pubmed:meshHeading |
pubmed-meshheading:17955214-Animals,
pubmed-meshheading:17955214-Behavior, Animal,
pubmed-meshheading:17955214-Catalase,
pubmed-meshheading:17955214-Corpus Striatum,
pubmed-meshheading:17955214-Dehydroepiandrosterone Sulfate,
pubmed-meshheading:17955214-Dopamine,
pubmed-meshheading:17955214-Dose-Response Relationship, Drug,
pubmed-meshheading:17955214-Dyskinesia, Drug-Induced,
pubmed-meshheading:17955214-Female,
pubmed-meshheading:17955214-Haloperidol,
pubmed-meshheading:17955214-Homovanillic Acid,
pubmed-meshheading:17955214-Injections, Intraperitoneal,
pubmed-meshheading:17955214-Lipid Peroxidation,
pubmed-meshheading:17955214-Male,
pubmed-meshheading:17955214-Mastication,
pubmed-meshheading:17955214-Norepinephrine,
pubmed-meshheading:17955214-Pregnanolone,
pubmed-meshheading:17955214-Pregnenolone,
pubmed-meshheading:17955214-Progesterone,
pubmed-meshheading:17955214-Rats,
pubmed-meshheading:17955214-Rats, Wistar,
pubmed-meshheading:17955214-Serotonin,
pubmed-meshheading:17955214-Superoxide Dismutase,
pubmed-meshheading:17955214-Superoxides
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pubmed:year |
2008
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pubmed:articleTitle |
Modulatory effect of neurosteroids in haloperidol-induced vacuous chewing movements and related behaviors.
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pubmed:affiliation |
Centre with Potential for Excellence in Biomedical Sciences, Panjab University, Chandigarh 160014, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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