| pubmed-article:17954522 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17954522 | lifeskim:mentions | umls-concept:C0700038 | lld:lifeskim |
| pubmed-article:17954522 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
| pubmed-article:17954522 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:17954522 | lifeskim:mentions | umls-concept:C0084692 | lld:lifeskim |
| pubmed-article:17954522 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:17954522 | lifeskim:mentions | umls-concept:C1515655 | lld:lifeskim |
| pubmed-article:17954522 | pubmed:issue | 12 | lld:pubmed |
| pubmed-article:17954522 | pubmed:dateCreated | 2007-12-21 | lld:pubmed |
| pubmed-article:17954522 | pubmed:abstractText | Surfactant protein D (SP-D) plays a role in innate immunity in the lung and is expressed at many other mucosal surfaces throughout the human body. In this study, we show that SP-D mRNA and protein are present in the murine female reproductive tract; i.e. in the vagina, cervix, uterus and oviduct. SP-D protein is primarily localized to epithelial cells lining the genital tract and is also present in secretory material within the lumen of the uterus and cervix. The levels of SP-D mRNA in the uterus vary by a factor of 10 during the estrous cycle with peak levels present at estrus and the lowest levels at diestrus. In contrast, SP-D mRNA levels in the lung do not change during the estrous cycle. Since SP-D is an innate host defense protein present in the mouse reproductive tract, we studied the influence of infection on SP-D levels in vivo. We found that Chlamydia muridarum infection caused an increase in the SP-D protein content of reproductive tract epithelial cells. These data are suggestive that SP-D may play a role in innate immunity in the female reproductive tract in vivo. | lld:pubmed |
| pubmed-article:17954522 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17954522 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17954522 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17954522 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17954522 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17954522 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17954522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17954522 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17954522 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17954522 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:17954522 | pubmed:issn | 1460-2407 | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:SnyderJeanne... | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:HoffmannDarre... | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:RamseyKyle... | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:AultKevin AKA | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:OberleyRebecc... | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:GossKelli LKL | lld:pubmed |
| pubmed-article:17954522 | pubmed:author | pubmed-author:NeffTraci LTL | lld:pubmed |
| pubmed-article:17954522 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:17954522 | pubmed:volume | 13 | lld:pubmed |
| pubmed-article:17954522 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17954522 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17954522 | pubmed:pagination | 863-8 | lld:pubmed |
| pubmed-article:17954522 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:meshHeading | pubmed-meshheading:17954522... | lld:pubmed |
| pubmed-article:17954522 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17954522 | pubmed:articleTitle | Regulation of surfactant protein D in the mouse female reproductive tract in vivo. | lld:pubmed |
| pubmed-article:17954522 | pubmed:affiliation | Department of Medicine, National Jewish Medical and Research Center, Denver, CO 80206, USA. oberleyr@njc.org | lld:pubmed |
| pubmed-article:17954522 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17954522 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
| entrez-gene:20390 | entrezgene:pubmed | pubmed-article:17954522 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:17954522 | lld:entrezgene |
