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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-10-23
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pubmed:abstractText |
Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant hereditary disorder associated with mutations of the MEN1 gene. MEN1 may present as a familial or a sporadic disorder, with multiple endocrine tumours including parathyroid adenomas or hyperplasias, and pancreatic endocrine and pituitary gland tumours. The aim of this study was to examine the prevalence and spectrum of MEN1 gene mutations in Hungarian patients with familial and sporadic MEN1 and in those with a MEN1-related state.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0300-0664
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
727-34
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17953629-Adolescent,
pubmed-meshheading:17953629-Adult,
pubmed-meshheading:17953629-Aged,
pubmed-meshheading:17953629-Aged, 80 and over,
pubmed-meshheading:17953629-Base Sequence,
pubmed-meshheading:17953629-Case-Control Studies,
pubmed-meshheading:17953629-DNA Mutational Analysis,
pubmed-meshheading:17953629-Evolution, Molecular,
pubmed-meshheading:17953629-Female,
pubmed-meshheading:17953629-Genetic Testing,
pubmed-meshheading:17953629-Germ-Line Mutation,
pubmed-meshheading:17953629-Heterozygote,
pubmed-meshheading:17953629-Humans,
pubmed-meshheading:17953629-Hungary,
pubmed-meshheading:17953629-Male,
pubmed-meshheading:17953629-Middle Aged,
pubmed-meshheading:17953629-Molecular Sequence Data,
pubmed-meshheading:17953629-Multiple Endocrine Neoplasia Type 1,
pubmed-meshheading:17953629-Mutation, Missense,
pubmed-meshheading:17953629-Phenotype,
pubmed-meshheading:17953629-Polymerase Chain Reaction,
pubmed-meshheading:17953629-Polymorphism, Genetic,
pubmed-meshheading:17953629-Sequence Alignment
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pubmed:year |
2007
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pubmed:articleTitle |
MEN1 gene mutations in Hungarian patients with multiple endocrine neoplasia type 1.
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pubmed:affiliation |
2nd Department of Medicine, Faculty of Medicine, Semmelweis Unievrsity, Budapest, Hungary.
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pubmed:publicationType |
Journal Article
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