Source:http://linkedlifedata.com/resource/pubmed/id/17950957
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2008-6-2
|
| pubmed:abstractText |
A new quaternary ammonium compound, bis-[2-hydroxy-3-(1,7,8,9,10-pentamethyl-3,5-dioxo-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-en-4-yloxy)-propyl]-dimethyl-ammonium chloride (4), was synthesized. The compound was investigated for antibacterial activity, including Gram-positive cocci and Gram-negative rods, and antifungal activity. Compound 4 showed significant inhibition against Staphylococcus aureus. Research was carried out over 4 standard strains and 40 hospital strains. Elementary analysis and/or MS, (1)H NMR and (13)C NMR spectra confirmed the identity of the products. The molecular structure of 3 was determined by an X-ray analysis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0223-5234
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1309-14
|
| pubmed:meshHeading |
pubmed-meshheading:17950957-Ammonium Chloride,
pubmed-meshheading:17950957-Anti-Bacterial Agents,
pubmed-meshheading:17950957-Culture Media,
pubmed-meshheading:17950957-Magnetic Resonance Spectroscopy,
pubmed-meshheading:17950957-Mass Spectrometry,
pubmed-meshheading:17950957-Microbial Sensitivity Tests,
pubmed-meshheading:17950957-Models, Molecular,
pubmed-meshheading:17950957-Molecular Structure
|
| pubmed:year |
2008
|
| pubmed:articleTitle |
Synthesis and antibacterial activity of bis-[2-hydroxy-3-(1,7,8,9,10-pentamethyl-3,5-dioxo-4-aza-tricyclo[5.2.1.0(2,6)]dec-8-en-4-yloxy)-propyl]-dimethyl-ammonium chloride.
|
| pubmed:affiliation |
Medical University, Department of Medical Chemistry, 3 Oczki Street, 02-007 Warsaw, Poland. strugam@wp.pl
|
| pubmed:publicationType |
Journal Article
|