Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-10-23
pubmed:abstractText
Low Frequency (<<100Hz) applied electric fields have been shown to modulate neuronal activity both In Vitro and in acute whole animal studies. We have been working to apply this technology for seizure control in chronically implanted animals. We have developed electronics for simultaneously recording neural activity while stimulating with low frequency fields. We have observed transient entrainment of spike and wave activity during spontaneous seizures with open loop sinusoidal stimulation with frequencies between 9-15 Hz. This is the first demonstration of low frequency field modulation of neural activity in chronically implanted mammalian brain.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1612-5
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Seizure modulation with applied electric fields in chronically implanted animals.
pubmed:affiliation
Dept. of Eng. Sci. & Mech., Pennsylvania State Univ., University Park, PA, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural