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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2007-10-23
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pubmed:abstractText |
A synthetic vector that transform from a cationic to an anionic lipid intracellularly is described. This charge-reversal lipid was synthesized and characterized, including the supramolecular complex it forms with DNA. Enhanced gene transfection was observed using this synthetic vector compared to current cationic lipids.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1557-170X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4347-9
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pubmed:meshHeading |
pubmed-meshheading:17946624-Animals,
pubmed-meshheading:17946624-Anions,
pubmed-meshheading:17946624-CHO Cells,
pubmed-meshheading:17946624-Cricetinae,
pubmed-meshheading:17946624-Cricetulus,
pubmed-meshheading:17946624-DNA,
pubmed-meshheading:17946624-Gene Transfer Techniques,
pubmed-meshheading:17946624-Genetic Vectors,
pubmed-meshheading:17946624-Humans,
pubmed-meshheading:17946624-K562 Cells,
pubmed-meshheading:17946624-Light,
pubmed-meshheading:17946624-Lipids,
pubmed-meshheading:17946624-Microscopy, Electron, Transmission,
pubmed-meshheading:17946624-Scattering, Radiation,
pubmed-meshheading:17946624-X-Ray Diffraction
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pubmed:year |
2006
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pubmed:articleTitle |
Non-viral charge reversal vectors for pDNA delivery.
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pubmed:affiliation |
Dept. of Biomed. Eng., Boston Univ., MA 02215, USA. cprata@bu.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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