Linked Life Data

17945813

Source:http://linkedlifedata.com/resource/pubmed/id/17945813

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-10-23
pubmed:abstractText
A bidomain reaction-diffusion model of the human heart was developed and potentials resulting from normal depolarization and repolarization were compared with results from a compatible monodomain model. Comparisons were made for an empty isolated heart and for a heart with fluid-filled ventricles. Both sinus rhythm and ectopic activation were simulated. The model took 2 days on 32 processors to simulate a complete cardiac cycle. Differences between monodomain and bidomain results were very small, even for the extracellular potentials which, for the monodomain model, were computed with a high-resolution forward model. Electrograms computed with monodomain and bidomain models were visually indistinguishable. We conclude that, in the absence of applied currents, propagating action potentials on the scale of a human heart can be studied with a monodomain model.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3895-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
A comparison of monodomain and bidomain propagation models for the human heart.
pubmed:affiliation
Res. Center, Hosp. du Sacre-Coeur de Montreal, Que. mark@potse.nl
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't