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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2008-6-20
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pubmed:abstractText |
Gallbladder carcinoma (GBC) usually arises in the background of gallstone disease which may be causatively related to decreased gallbladder contractility. Cholecystokinin receptor A (CCK-AR) mediates signals resulting in gallbladder contraction. Deteriorating gallbladder contraction promotes gallstone formation. A common genetic polymorphism of CCK-AR may be causatively associated with the risk of gallstone and GBC. This study aimed to understand the association of CCK-AR Pst I polymorphism in gallstone disease with gallbladder cancer.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1440-1746
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
970-5
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pubmed:meshHeading |
pubmed-meshheading:17944886-Adult,
pubmed-meshheading:17944886-Case-Control Studies,
pubmed-meshheading:17944886-Confidence Intervals,
pubmed-meshheading:17944886-Female,
pubmed-meshheading:17944886-Gallbladder Neoplasms,
pubmed-meshheading:17944886-Gallstones,
pubmed-meshheading:17944886-Genetic Predisposition to Disease,
pubmed-meshheading:17944886-Humans,
pubmed-meshheading:17944886-India,
pubmed-meshheading:17944886-Male,
pubmed-meshheading:17944886-Middle Aged,
pubmed-meshheading:17944886-Odds Ratio,
pubmed-meshheading:17944886-Polymorphism, Genetic,
pubmed-meshheading:17944886-Receptor, Cholecystokinin A,
pubmed-meshheading:17944886-Risk Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Cholecystokinin receptor A gene polymorphism in gallstone disease and gallbladder cancer.
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pubmed:affiliation |
Departments of Genetics, Sanjay Gandi Post Graduate Institute of Medical Sciences, Lucknow, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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