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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1992-4-9
|
| pubmed:abstractText |
The genes ces-1 and ces-2 control the decisions of two cells in the nematode Caenorhabditis elegans to undergo programmed cell death. Mutations that cause a gain of ces-1 function or a reduction of ces-2 function prevent these cells, the sisters of the two pharyngeal NSM neurons, from dying. These mutations do not affect most other cell deaths. Genetic studies indicate that ces-1 and ces-2 affect the fates of the NSM sisters by regulating the genes required for all programmed cell deaths to occur.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0950-1991
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
112
|
| pubmed:geneSymbol |
ces-1,
ces-2
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
591-603
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1794327-Animals,
pubmed-meshheading:1794327-Caenorhabditis,
pubmed-meshheading:1794327-Cell Survival,
pubmed-meshheading:1794327-Chromosome Mapping,
pubmed-meshheading:1794327-Genes, Regulator,
pubmed-meshheading:1794327-Genotype,
pubmed-meshheading:1794327-Mutagenesis,
pubmed-meshheading:1794327-Pharynx,
pubmed-meshheading:1794327-Phenotype
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Two C. elegans genes control the programmed deaths of specific cells in the pharynx.
|
| pubmed:affiliation |
Howard Hughes Medical Institute, Department of Biology, M.I.T. Cambridge 02139.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|