Linked Life Data

17942721

Source:http://linkedlifedata.com/resource/pubmed/id/17942721

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
42
pubmed:dateCreated
2007-10-18
pubmed:abstractText
Asymmetry of spatial attention has long been described in both disease (hemispatial neglect) and healthy (pseudoneglect) states. Although right-hemisphere specialization for spatial attention has been suggested, the exact neural mechanisms of asymmetry have not been deciphered yet. A recent functional magnetic resonance imaging study from our laboratory serendipitously revealed bihemispheric left-hemifield superiority in activation of a visuospatial attention-related network. Nineteen right-handed healthy adult females participated in two experiments of visual half-field presentation. Either facial expressions (experiment 1) or house images (experiment 2) were presented unilaterally and parafoveally for 150 ms while subjects were engaging a central fixation task. Brain regions previously associated with a visuospatial attention network, in both hemispheres, were found to be more robustly activated by left visual field stimuli. The consistency of this finding with manifestations of attention lateralization is discussed, and a revised model based on neural connectivity asymmetry is proposed. Support for the revised model is given by a dynamic causal modeling analysis. Unraveling the basis for attention asymmetry may lead to better understanding of the pathogenesis of attention disorders, followed by improved diagnosis and treatment. Additionally, the proposed model for asymmetry of visuospatial attention might provide important insights into the mechanisms underlying functional brain lateralization in general.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
17
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
11271-8
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Bihemispheric leftward bias in a visuospatial attention-related network.
pubmed:affiliation
Functional Brain Imaging Unit, Wohl Institute for Advanced Imaging, Tel Aviv Sourasky Medical Center, Tel Aviv 64239, Israel.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't