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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3-4
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pubmed:dateCreated |
2007-10-17
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pubmed:abstractText |
Early identification of chemoresistance in patients with ovarian cancer is of utmost importance in order to provide them with the most appropriate therapy. Recently, we described the expression of MyD88 in ovarian cancer cells that were resistant to the cytotoxic agent paclitaxel. In addition to chemoresistance, in MyD88 positive ovarian cancer cells, paclitaxel stimulates growth and production of proinflammatory cytokines. The objective of this study was to determine the correlation of MyD88 expression in primary and recurrent epithelial ovarian cancers with the response to carboplatin and paclitaxel combination chemotherapy.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-10445423,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-10963636,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-11280739,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-11445667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-11500829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-11775463,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-11948342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-12860964,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-14500397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-14675308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-14751757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-14976262,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-16153858,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-16388521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-16585214,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-16786039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-16815388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-17217363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17940625-1970196
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1551-4056
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-63
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17940625-Antineoplastic Agents, Phytogenic,
pubmed-meshheading:17940625-Disease-Free Survival,
pubmed-meshheading:17940625-Drug Resistance, Neoplasm,
pubmed-meshheading:17940625-Female,
pubmed-meshheading:17940625-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17940625-Humans,
pubmed-meshheading:17940625-Lasers,
pubmed-meshheading:17940625-Microdissection,
pubmed-meshheading:17940625-Myeloid Differentiation Factor 88,
pubmed-meshheading:17940625-Ovarian Neoplasms,
pubmed-meshheading:17940625-Paclitaxel,
pubmed-meshheading:17940625-Treatment Outcome,
pubmed-meshheading:17940625-Tumor Cells, Cultured
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pubmed:year |
2006
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pubmed:articleTitle |
MyD88 predicts chemoresistance to paclitaxel in epithelial ovarian cancer.
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pubmed:affiliation |
Department of Obstetrics, Gynecology, and Reproductive Services, Yale University School of Medicine, New Haven, Connecticut 06520, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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