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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-10-16
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pubmed:abstractText |
[N-methyl-(11)C]2-(4'-(methylaminophenyl)-benzothiazole ((11)C-BTA-1) is a thioflavin-T derivative that has been one of the promising PET tracers for imaging of amyloid plaque distribution in the Alzheimer patients brain in vivo. The biodistribution and dosimetry of this tracer in humans is presented and compared to the results of a previous dosimetry and biodistribution study of another thioflavin-T derivative [N-methyl-(11)C]2-hydroxy-(4'-(methylaminophenyl)-benzothiazole ((11)C-OH-BTA-1) in baboons.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0029-5566
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175-80
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17938750-Adult,
pubmed-meshheading:17938750-Alzheimer Disease,
pubmed-meshheading:17938750-Amyloid beta-Peptides,
pubmed-meshheading:17938750-Bone Marrow,
pubmed-meshheading:17938750-Brain,
pubmed-meshheading:17938750-Carbon Radioisotopes,
pubmed-meshheading:17938750-Female,
pubmed-meshheading:17938750-Gallbladder,
pubmed-meshheading:17938750-Heart,
pubmed-meshheading:17938750-Humans,
pubmed-meshheading:17938750-Kidney,
pubmed-meshheading:17938750-Liver,
pubmed-meshheading:17938750-Lung,
pubmed-meshheading:17938750-Male,
pubmed-meshheading:17938750-Positron-Emission Tomography,
pubmed-meshheading:17938750-Reference Values,
pubmed-meshheading:17938750-Tissue Distribution,
pubmed-meshheading:17938750-Urinary Bladder
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pubmed:year |
2007
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pubmed:articleTitle |
Radiation dosimetry and biodistribution of the beta-amyloid plaque imaging tracer 11C-BTA-1 in humans.
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pubmed:affiliation |
Klinik für Nuklearmedizin, Universität Ulm, Robert-Koch-Str. 8, 89081 Ulm, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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