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pubmed-article:17936889pubmed:abstractTextRNA interference is an endogenous cellular mechanism in which short interfering RNAs (siRNAs) direct the sequence specific degradation of a target mRNA. siRNAs can be synthesized with chemical modifications to increase stability and reduce double-stranded RNA-induced immune responses without affecting their ability to elicit degradation of target mRNA.lld:pubmed
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pubmed-article:17936889pubmed:articleTitleEffect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice.lld:pubmed
pubmed-article:17936889pubmed:affiliationDivision of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO 80206, USA.lld:pubmed
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