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17936624
Source:
http://linkedlifedata.com/resource/pubmed/id/17936624
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pubmed-article:17936624
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pubmed-article:17936624
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pubmed-article:17936624
pubmed:issue
23
lld:pubmed
pubmed-article:17936624
pubmed:dateCreated
2007-11-6
lld:pubmed
pubmed-article:17936624
pubmed:abstractText
We describe three novel regioisomeric series of aryl naphthyridine analogs, which are potent antagonists of the Class III GPCR mGlu5 receptor. The synthesis and in vitro and in vivo pharmacological activities of these analogs are discussed.
lld:pubmed
pubmed-article:17936624
pubmed:language
eng
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pubmed-article:17936624
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IM
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pubmed:status
MEDLINE
lld:pubmed
pubmed-article:17936624
pubmed:month
Dec
lld:pubmed
pubmed-article:17936624
pubmed:issn
1464-3405
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pubmed-article:17936624
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pubmed:issnType
Electronic
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pubmed:day
1
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pubmed:volume
17
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pubmed:owner
NLM
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pubmed-article:17936624
pubmed:authorsComplete
Y
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pubmed-article:17936624
pubmed:pagination
6525-8
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pubmed-article:17936624
pubmed:year
2007
lld:pubmed
pubmed-article:17936624
pubmed:articleTitle
Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists.
lld:pubmed
pubmed-article:17936624
pubmed:affiliation
Department of Medicinal Chemistry, Pfizer Global Research & Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.
lld:pubmed
pubmed-article:17936624
pubmed:publicationType
Journal Article
lld:pubmed
pubmed-article:17936624
pubmed:publicationType
Comparative Study
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