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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19
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pubmed:dateCreated |
2007-10-15
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pubmed:abstractText |
The delivery of glucose from the blood to the brain involves its passage across the endothelial cells of the blood-brain barrier (BBB), which is mediated by the facilitative glucose transporter protein 1 (GLUT(1)), and then across the neural cell membranes, which is mediated by GLUT(3). This study aimed to evaluate the dynamic influence of hyperglycemia on the expression of these GLUTs by measuring their expression in the brain at different blood glucose levels in a rat model of diabetes. This might help to determine the proper blood glucose threshold level in the treatment of diabetic apoplexy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0366-6999
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pubmed:author |
pubmed-author:ChenLiL,
pubmed-author:FuChun-liCL,
pubmed-author:HouWei-kaiWK,
pubmed-author:HouXin-guoXG,
pubmed-author:LaiHongH,
pubmed-author:SongJunJ,
pubmed-author:XianYu-xinYX,
pubmed-author:XuFu-yuFY,
pubmed-author:XuYu-xinYX,
pubmed-author:YuTingT,
pubmed-author:ZhangLiL,
pubmed-author:ZhangWen-wenWW
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pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
120
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1704-9
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pubmed:meshHeading |
pubmed-meshheading:17935675-Animals,
pubmed-meshheading:17935675-Blood Glucose,
pubmed-meshheading:17935675-Brain,
pubmed-meshheading:17935675-Diabetes Mellitus, Experimental,
pubmed-meshheading:17935675-Glucose Transporter Type 1,
pubmed-meshheading:17935675-Glucose Transporter Type 3,
pubmed-meshheading:17935675-Hemoglobin A, Glycosylated,
pubmed-meshheading:17935675-Male,
pubmed-meshheading:17935675-RNA, Messenger,
pubmed-meshheading:17935675-Rats,
pubmed-meshheading:17935675-Rats, Wistar,
pubmed-meshheading:17935675-Streptozocin
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pubmed:year |
2007
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pubmed:articleTitle |
Influence of blood glucose on the expression of glucose trans-porter proteins 1 and 3 in the brain of diabetic rats.
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pubmed:affiliation |
Department of Endocrinology, Qilu Hospital of Shandong University, Jinan 250012, China.
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pubmed:publicationType |
Journal Article
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