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rdf:type |
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lifeskim:mentions |
umls-concept:C0005404,
umls-concept:C0012655,
umls-concept:C0017337,
umls-concept:C0026809,
umls-concept:C0086418,
umls-concept:C0205419,
umls-concept:C0242216,
umls-concept:C0521447,
umls-concept:C0597357,
umls-concept:C0679058,
umls-concept:C1417825,
umls-concept:C1547699,
umls-concept:C2700640
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-10
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pubmed:abstractText |
From quantitative trait locus mapping in inbred mice, we identified the Nr1h4 gene encoding the nuclear bile salt receptor FXR as a candidate gene for the cholesterol gallstone susceptibility locus Lith7. Here, we investigated further an association of the gene encoding FXR and gallstone susceptibility in mice and humans.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:BockHans HHH,
pubmed-author:KovacsPeterP,
pubmed-author:KressRahelR,
pubmed-author:KurtzUlrikeU,
pubmed-author:LammertFrankF,
pubmed-author:Méndez-SánchezNahumN,
pubmed-author:MössnerJoachimJ,
pubmed-author:MiquelJuan FranciscoJF,
pubmed-author:NerviFlavioF,
pubmed-author:RochaJacquelineJ,
pubmed-author:Schirin-SokhanRaminR,
pubmed-author:StumvollMichaelM,
pubmed-author:UribeMisaelM,
pubmed-author:WittenburgHenningH
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
116-24
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pubmed:meshHeading |
pubmed-meshheading:17931734-Alleles,
pubmed-meshheading:17931734-Animals,
pubmed-meshheading:17931734-Body Mass Index,
pubmed-meshheading:17931734-Chile,
pubmed-meshheading:17931734-Chromosome Mapping,
pubmed-meshheading:17931734-DNA-Binding Proteins,
pubmed-meshheading:17931734-Diet,
pubmed-meshheading:17931734-Ethnic Groups,
pubmed-meshheading:17931734-Female,
pubmed-meshheading:17931734-Gallstones,
pubmed-meshheading:17931734-Gene Expression Regulation,
pubmed-meshheading:17931734-Genotype,
pubmed-meshheading:17931734-Germany,
pubmed-meshheading:17931734-Humans,
pubmed-meshheading:17931734-Male,
pubmed-meshheading:17931734-Mexico,
pubmed-meshheading:17931734-Mice,
pubmed-meshheading:17931734-Middle Aged,
pubmed-meshheading:17931734-Polymorphism, Single Nucleotide,
pubmed-meshheading:17931734-RNA, Messenger,
pubmed-meshheading:17931734-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:17931734-Transcription Factors
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pubmed:year |
2008
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pubmed:articleTitle |
Variation of the gene encoding the nuclear bile salt receptor FXR and gallstone susceptibility in mice and humans.
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pubmed:affiliation |
University of Leipzig, Department of Medicine III, Leipzig, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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