Linked Life Data

17928397

Source:http://linkedlifedata.com/resource/pubmed/id/17928397

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-12-31
pubmed:abstractText
In this study, we asked whether a possible quantitative or qualitative deficiency in naturally occurring Foxp3(+)CD4(+) regulatory T-cells (nT(reg)), which display potent inhibitory effects on T-cell functions in vitro and in vivo, may predispose to the development of type 1 diabetes.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1939-327X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
113-23
pubmed:dateRevised
2008-3-21
pubmed:meshHeading
pubmed-meshheading:17928397-Adoptive Transfer, pubmed-meshheading:17928397-Animals, pubmed-meshheading:17928397-CD4-Positive T-Lymphocytes, pubmed-meshheading:17928397-Cell Division, pubmed-meshheading:17928397-Cytokines, pubmed-meshheading:17928397-Diabetes Mellitus, Type 1, pubmed-meshheading:17928397-Forkhead Transcription Factors, pubmed-meshheading:17928397-Islets of Langerhans, pubmed-meshheading:17928397-Ki-67 Antigen, pubmed-meshheading:17928397-Lymphocyte Count, pubmed-meshheading:17928397-Male, pubmed-meshheading:17928397-Mice, pubmed-meshheading:17928397-Mice, Inbred C57BL, pubmed-meshheading:17928397-Mice, Inbred NOD, pubmed-meshheading:17928397-Pancreas, pubmed-meshheading:17928397-Phenotype, pubmed-meshheading:17928397-T-Lymphocyte Subsets, pubmed-meshheading:17928397-T-Lymphocytes, Regulatory
pubmed:year
2008
pubmed:articleTitle
Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.
pubmed:affiliation
Department of Microbiology and Immunology, McGill Center for the Study of Host Resistance, McGill University, 3775 University St., Room 510, Lyman Duff Medical Building, Montreal, QC, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't