Linked Life Data

17926867

Source:http://linkedlifedata.com/resource/pubmed/id/17926867

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
16
pubmed:dateCreated
2007-10-11
pubmed:abstractText
Blood lactate and pyruvate levels and lactate-pyruvate ratios were determined in 20 patients with severe hypoxemia due to pulmonary insufficiency, 18 patients having arterial oxygen tensions (pO2) lower than 50 mm. of mercury, and 8 having tensions lower than 40 mm. of mercury. Most of the patients had normal lactate levels and lactate-pyruvate ratios in spite of severe hypoxemia, and there was no correlation between pO2 or oxygen content and raised levels. All but 1 patient with an elevated lactate level and lactate-pyruvate ratio had a disorder of systemic circulation with hypotension. On the other hand, failure of the right side of the heart with cor pulmonale did not lead to hyperlactatemia. In the resting state generalized tissue hypoxia and increased anaerobic metabolism are seldom due to clinical hypoxemia per se. When present, increased anaerobic metabolism is related to a systemic circulatory disorder, with resultant inadequate tissue perfusion.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0028-4793
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
274
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
878-83
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1966
pubmed:articleTitle
Blood lactate and pyruvate in pulmonary insufficiency.
pubmed:affiliation
Department of Medicine, Stanford University School of Medicine, California, USA.
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural