rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2007-10-10
|
pubmed:abstractText |
The origin of metazoan development and differentiation was contingent upon the evolution of cell adhesion, communication and cooperation mechanisms. While components of many of the major cell signalling pathways have been identified in a range of sponges (phylum Porifera), their roles in development have not been investigated and remain largely unknown. Here, we take the first steps toward reconstructing the developmental signalling systems used in the last common ancestor to living sponges and eumetazoans by studying the expression of genes encoding Wnt and TGF-beta signalling ligands during the embryonic development of a sponge.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925879-10405173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925879-10431240,
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1932-6203
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
2
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
e1031
|
pubmed:dateRevised |
2010-9-16
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pubmed:meshHeading |
pubmed-meshheading:17925879-Animals,
pubmed-meshheading:17925879-Body Patterning,
pubmed-meshheading:17925879-Cell Adhesion,
pubmed-meshheading:17925879-Cell Differentiation,
pubmed-meshheading:17925879-DNA, Complementary,
pubmed-meshheading:17925879-Gene Expression Regulation, Developmental,
pubmed-meshheading:17925879-In Situ Hybridization,
pubmed-meshheading:17925879-Ligands,
pubmed-meshheading:17925879-Models, Biological,
pubmed-meshheading:17925879-Phylogeny,
pubmed-meshheading:17925879-Porifera,
pubmed-meshheading:17925879-Signal Transduction,
pubmed-meshheading:17925879-Transforming Growth Factor beta,
pubmed-meshheading:17925879-Wnt Proteins
|
pubmed:year |
2007
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pubmed:articleTitle |
Wnt and TGF-beta expression in the sponge Amphimedon queenslandica and the origin of metazoan embryonic patterning.
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pubmed:affiliation |
School of Integrative Biology, The University of Queensland, Brisbane, Queensland, Australia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|