|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2007-10-10
|
|
pubmed:abstractText |
Traditional imaging techniques for the localization and monitoring of bacterial infections, although reasonably sensitive, suffer from a lack of specificity. This is particularly true for musculoskeletal infections. Bacteria possess a thymidine kinase (TK) whose substrate specificity is distinct from that of the major human TK. The substrate specificity difference has been exploited to develop a new imaging technique that can detect the presence of viable bacteria.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-11337525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-11871805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-11914892,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-12791820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-12902430,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-14990668,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15094447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15129706,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15175400,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15471990,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15534056,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15653773,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-15809477,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16162850,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16434514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16595481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16721569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16770299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16770303,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16770305,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-16969256,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-17142443,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-17332288,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-17401105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-2266391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-7444348,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-8551884,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-8726039,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-9079672,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17925855-9220443
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1932-6203
|
|
pubmed:author |
pubmed-author:AgrawalNishantN,
pubmed-author:BettegowdaChetanC,
pubmed-author:CheongIanI,
pubmed-author:ConwayJanetJ,
pubmed-author:DiazLuis ALAJr,
pubmed-author:EndresChristopher JCJ,
pubmed-author:FossCatherine ACA,
pubmed-author:KinzlerKenneth WKW,
pubmed-author:LadensonPaul WPW,
pubmed-author:MontMichael AMA,
pubmed-author:NimmagaddaSridharS,
pubmed-author:PomperMartin GMG,
pubmed-author:SeylerThorsten MTM,
pubmed-author:ThorntonKatherineK,
pubmed-author:UlrichSlif DSD,
pubmed-author:UzunerOvsevO,
pubmed-author:VogelsteinBarry NBN,
pubmed-author:VogelsteinBertB,
pubmed-author:ZhangXiaosongX,
pubmed-author:ZhouShibinS
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
2
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
e1007
|
|
pubmed:meshHeading |
pubmed-meshheading:17925855-Arabinofuranosyluracil,
pubmed-meshheading:17925855-Bacteria,
pubmed-meshheading:17925855-Bacterial Infections,
pubmed-meshheading:17925855-Bone and Bones,
pubmed-meshheading:17925855-Case-Control Studies,
pubmed-meshheading:17925855-Diagnostic Imaging,
pubmed-meshheading:17925855-Humans,
pubmed-meshheading:17925855-Muscles,
pubmed-meshheading:17925855-Positron-Emission Tomography,
pubmed-meshheading:17925855-Radiopharmaceuticals,
pubmed-meshheading:17925855-Substrate Specificity,
pubmed-meshheading:17925855-Thymidine Kinase,
pubmed-meshheading:17925855-Tomography, X-Ray Computed
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT.
|
|
pubmed:affiliation |
The Howard Hughes Medical Institute, The Ludwig Center for Cancer Genetics and Therapeutics at Johns Hopkins, Baltimore, Maryland, United States of America.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
