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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-10-9
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pubmed:abstractText |
Mice with a knockout (KO) of muscle LIM protein (MLP) exhibit many morphologic and clinical features of human cardiomyopathy. In humans, MLP-expression is downregulated both in ischemic and dilative cardiomyopathy. In this study, we investigated the effects of MLP on the electrophysiologic phenotype in vivo and on outward potassium currents.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1532-8414
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pubmed:author |
pubmed-author:DurgacTolgaT,
pubmed-author:GardiwalAjmalA,
pubmed-author:HeinekeJoergJ,
pubmed-author:KleinGunnarG,
pubmed-author:KoenigThorbenT,
pubmed-author:KorteThomasT,
pubmed-author:KraemerKirstenK,
pubmed-author:KrampflKlausK,
pubmed-author:MohammadiBahramB,
pubmed-author:NiehausMichaelM,
pubmed-author:SchaeferArndA,
pubmed-author:WollertKai CKC
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pubmed:issnType |
Electronic
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
687-93
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17923363-Animals,
pubmed-meshheading:17923363-Delayed Rectifier Potassium Channels,
pubmed-meshheading:17923363-Electrophysiology,
pubmed-meshheading:17923363-Female,
pubmed-meshheading:17923363-LIM Domain Proteins,
pubmed-meshheading:17923363-Male,
pubmed-meshheading:17923363-Mice,
pubmed-meshheading:17923363-Mice, Knockout,
pubmed-meshheading:17923363-Muscle Proteins,
pubmed-meshheading:17923363-Ventricular Dysfunction, Left,
pubmed-meshheading:17923363-Ventricular Function
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pubmed:year |
2007
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pubmed:articleTitle |
Reduced delayed rectifier K+ current, altered electrophysiology, and increased ventricular vulnerability in MLP-deficient mice.
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pubmed:affiliation |
Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Comparative Study
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