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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2007-10-9
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pubmed:abstractText |
The differential diagnosis of eosinophilic renal tumors can be difficult by light microscopy. In particular, chromophobe renal cell carcinoma (RCC) is difficult to distinguish from oncocytoma. This differential diagnosis is important because chromophobe RCC is malignant, whereas oncocytoma is benign. Furthermore, chromophobe RCC has distinct malignant potential and prognosis compared with eosinophilic variants of other RCC subtypes. Immunohistochemistry is useful for distinguishing chromophobe RCC from other subtypes of renal carcinoma, but no expression marker reliably separates chromophobe RCC from oncocytoma.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1543-2165
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
131
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1541-6
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17922590-Adenoma, Oxyphilic,
pubmed-meshheading:17922590-Carcinoma, Renal Cell,
pubmed-meshheading:17922590-Diagnosis, Differential,
pubmed-meshheading:17922590-Gene Expression,
pubmed-meshheading:17922590-Gene Expression Profiling,
pubmed-meshheading:17922590-Immunohistochemistry,
pubmed-meshheading:17922590-Kidney Neoplasms,
pubmed-meshheading:17922590-Membrane Proteins,
pubmed-meshheading:17922590-RNA, Messenger,
pubmed-meshheading:17922590-RNA, Neoplasm,
pubmed-meshheading:17922590-Tumor Markers, Biological
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pubmed:year |
2007
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pubmed:articleTitle |
Claudin-7 immunohistochemistry in renal tumors: a candidate marker for chromophobe renal cell carcinoma identified by gene expression profiling.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA 30303, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural,
Validation Studies
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