Source:http://linkedlifedata.com/resource/pubmed/id/17920885
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
23
|
| pubmed:dateCreated |
2007-11-6
|
| pubmed:abstractText |
Eight d-ribo-phytosphingosine derivatives were synthesized from d-ribo-phytosphingosine and diverse acyl chlorides with N,N-diisopropylethylamine in tetrahydrofuran for 1h at room temperature. Effect of these compounds on IR-induced cell death was evaluated on blood cancer cells (Jurkat). Among these, 3d showed the highest enhancement of radiosensitizing effect.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Dec
|
| pubmed:issn |
1464-3405
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:day |
1
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
6643-6
|
| pubmed:meshHeading |
pubmed-meshheading:17920885-Apoptosis,
pubmed-meshheading:17920885-Combined Modality Therapy,
pubmed-meshheading:17920885-Drug Evaluation, Preclinical,
pubmed-meshheading:17920885-Humans,
pubmed-meshheading:17920885-Jurkat Cells,
pubmed-meshheading:17920885-Leukemia, T-Cell,
pubmed-meshheading:17920885-Radiation-Sensitizing Agents,
pubmed-meshheading:17920885-Sphingosine
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Synthesis of novel phytosphingosine derivatives and their preliminary biological evaluation for enhancing radiation therapy.
|
| pubmed:affiliation |
Laboratory of Radiopharmaceuticals, Korea Institute of Radiological and Medical Sciences, 215-4 Gongneungdong, Nowongu, Seoul 139-706, Republic of Korea.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|