Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1992-3-31
|
| pubmed:abstractText |
A mutation within exon 17 at codon 717 of the beta-amyloid protein precursor (APP) gene is one cause of early onset familial Alzheimer's disease. Direct sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with familial early onset Alzheimer's disease without the known pathogenic mutation (APP717) failed to reveal other mutations within the beta-amyloid sequence in this form of the disorder.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0304-3940
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
25
|
| pubmed:volume |
133
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1-2
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1791986-Adult,
pubmed-meshheading:1791986-Aged,
pubmed-meshheading:1791986-Alzheimer Disease,
pubmed-meshheading:1791986-Amyloid beta-Protein Precursor,
pubmed-meshheading:1791986-Base Sequence,
pubmed-meshheading:1791986-Exons,
pubmed-meshheading:1791986-Humans,
pubmed-meshheading:1791986-Middle Aged,
pubmed-meshheading:1791986-Molecular Sequence Data,
pubmed-meshheading:1791986-Mutation
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence.
|
| pubmed:affiliation |
Department of Biochemistry, St. Mary's Hospital Medical School, London, U.K.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|