Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-10-8
pubmed:abstractText
The prognosis of high-grade oligodendroglioma has been reported poor with an average survival of approximately 17 months. Local recurrence after surgery is seen in about 50% of the patients, but distant extracranial metastases have been described rarely. Frequent extracranial metastases have been reported in the lungs, pleura, lymph nodes, bones, liver, adrenal glands, kidneys and other sites. We present a case of 16-year-old girl with high-grade oligodendroglioma who developed bilateral pulmonary metastases 19 months following complete resection of the primary brain tumor. She did not respond to first-line chemotherapy; however, the patient achieved an almost complete response with cisplatin (CDDP) and etoposide (VP-16) salvage chemotherapy. She remains well and asymptomatic 18 months after the end of chemotherapy. We herein review the literature and discuss all the possible mechanisms for extracranial dissemination of primary brain tumours.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1107-0625
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
273-6
pubmed:articleTitle
Successful management of extracranial metastases from cerebral high-grade oligodendroglioma: report of a case with literature review.
pubmed:affiliation
Department of Medical Oncology-A, Metaxa Cancer Hospital, Piraeus, Greece. pectasid@otenet.gr
pubmed:publicationType
Journal Article