17918267

Source:http://linkedlifedata.com/resource/pubmed/id/17918267

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0028944, umls-concept:C0038952, umls-concept:C0086418, umls-concept:C0231448, umls-concept:C0388088, umls-concept:C0870134, umls-concept:C1522240
pubmed:issue	1
pubmed:dateCreated	2008-2-4
pubmed:abstractText	FTY720, a sphingosine-1-phosphate (S1P) receptor agonist that crosses the blood-brain barrier, is a potential immuno-therapy for multiple sclerosis. Our objective was to assess the effect of FTY720 on process extension, differentiation, and survival of human oligodendrocyte progenitor cells (OPCs), and link the functional effects with S1P receptor expression and signaling.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R21 NS049014
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7707449
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Extracellular Signal-Regulated MAP..., http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents, http://linkedlifedata.com/resource/pubmed/chemical/Lysophospholipids, http://linkedlifedata.com/resource/pubmed/chemical/Propylene Glycols, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, G-Protein-Coupled, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Lysosphingolipid, http://linkedlifedata.com/resource/pubmed/chemical/Sphingosine, http://linkedlifedata.com/resource/pubmed/chemical/Suramin, http://linkedlifedata.com/resource/pubmed/chemical/fingolimod, http://linkedlifedata.com/resource/pubmed/chemical/rho-Associated Kinases, http://linkedlifedata.com/resource/pubmed/chemical/sphingosine 1-phosphate
pubmed:status	MEDLINE
pubmed:month	Jan
pubmed:issn	1531-8249
pubmed:author	pubmed-author:AntelJack PJP, pubmed-author:JungCha GyunCG, pubmed-author:KennedyTimothy ETE, pubmed-author:KimHye JungHJ, pubmed-author:MironVeronique EVE, pubmed-author:SolivenBettyB
pubmed:issnType	Electronic
pubmed:volume	63
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	61-71
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17918267-Cell Differentiation, pubmed-meshheading:17918267-Cell Line, pubmed-meshheading:17918267-Cell Movement, pubmed-meshheading:17918267-Cell Surface Extensions, pubmed-meshheading:17918267-Cell Survival, pubmed-meshheading:17918267-Cytoskeleton, pubmed-meshheading:17918267-Down-Regulation, pubmed-meshheading:17918267-Extracellular Signal-Regulated MAP Kinases, pubmed-meshheading:17918267-Humans, pubmed-meshheading:17918267-Immunosuppressive Agents, pubmed-meshheading:17918267-Lysophospholipids, pubmed-meshheading:17918267-Oligodendroglia, pubmed-meshheading:17918267-Propylene Glycols, pubmed-meshheading:17918267-RNA, Messenger, pubmed-meshheading:17918267-Receptors, G-Protein-Coupled, pubmed-meshheading:17918267-Receptors, Lysosphingolipid, pubmed-meshheading:17918267-Signal Transduction, pubmed-meshheading:17918267-Sphingosine, pubmed-meshheading:17918267-Stem Cells, pubmed-meshheading:17918267-Suramin, pubmed-meshheading:17918267-rho-Associated Kinases
pubmed:year	2008
pubmed:articleTitle	FTY720 modulates human oligodendrocyte progenitor process extension and survival.
pubmed:affiliation	Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural