Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2007-11-21
pubmed:abstractText
Statins have been shown to increase endothelial nitric oxide synthase expression via enhanced mRNA stability. Because the poly(A) tail is an important determinant of transcript stability, we sought to characterize the effect of statins on eNOS mRNA 3' polyadenylation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Cytochalasin D, http://linkedlifedata.com/resource/pubmed/chemical/Fluorobenzenes, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA..., http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III, http://linkedlifedata.com/resource/pubmed/chemical/Pyrimidines, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger, http://linkedlifedata.com/resource/pubmed/chemical/RNA Polymerase II, http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin, http://linkedlifedata.com/resource/pubmed/chemical/Sulfonamides, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha, http://linkedlifedata.com/resource/pubmed/chemical/rho GTP-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/rosuvastatin
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1524-4636
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2642-9
pubmed:meshHeading
pubmed-meshheading:17916773-Animals, pubmed-meshheading:17916773-Cattle, pubmed-meshheading:17916773-Cell Hypoxia, pubmed-meshheading:17916773-Cell Nucleus, pubmed-meshheading:17916773-Cells, Cultured, pubmed-meshheading:17916773-Cytochalasin D, pubmed-meshheading:17916773-Cytoplasm, pubmed-meshheading:17916773-Cytoskeleton, pubmed-meshheading:17916773-Dose-Response Relationship, Drug, pubmed-meshheading:17916773-Endothelial Cells, pubmed-meshheading:17916773-Fluorobenzenes, pubmed-meshheading:17916773-Gene Expression Regulation, Enzymologic, pubmed-meshheading:17916773-Hydroxymethylglutaryl-CoA Reductase Inhibitors, pubmed-meshheading:17916773-Nitric Oxide Synthase Type III, pubmed-meshheading:17916773-Phosphorylation, pubmed-meshheading:17916773-Pyrimidines, pubmed-meshheading:17916773-RNA, Messenger, pubmed-meshheading:17916773-RNA 3' Polyadenylation Signals, pubmed-meshheading:17916773-RNA Polymerase II, pubmed-meshheading:17916773-RNA Stability, pubmed-meshheading:17916773-Simvastatin, pubmed-meshheading:17916773-Sulfonamides, pubmed-meshheading:17916773-Time Factors, pubmed-meshheading:17916773-Tumor Necrosis Factor-alpha, pubmed-meshheading:17916773-rho GTP-Binding Proteins
pubmed:year
2007
pubmed:articleTitle
Statin treatment and 3' polyadenylation of eNOS mRNA.
pubmed:affiliation
Division of Cardiology, Emory University School of Medicine, 1639 Pierce Dr, WMB 319, Atlanta, GA 30322, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural