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pubmed-article:17916769pubmed:abstractTextWhereas growth factors, via their ability to stimulate vascular smooth muscle cell (VSMC) proliferation and migration, have been thought to play a permissive role in atherosclerosis initiation and progression, the role of insulin-like growth factor-1 (IGF-1) is unknown. Here we report for the first time that IGF-1 infusion decreased atherosclerotic plaque progression in ApoE-deficient mice on a Western diet.lld:pubmed
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pubmed-article:17916769pubmed:articleTitleIGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice.lld:pubmed
pubmed-article:17916769pubmed:affiliationCardiology Section, Department of Medicine, Tulane University School of Medicine, 1430 Tulane Ave, SL-48, New Orleans, LA 70112, USA.lld:pubmed
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pubmed-article:17916769pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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