|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005400,
umls-concept:C0017262,
umls-concept:C0023884,
umls-concept:C0032717,
umls-concept:C0034693,
umls-concept:C0078058,
umls-concept:C0185117,
umls-concept:C0205117,
umls-concept:C0227525,
umls-concept:C0752248,
umls-concept:C2911684
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|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2007-10-4
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|
pubmed:abstractText |
It would be of clinical importance to clarify molecular mechanisms of cholangiocytes proliferation for the treatment of intractable cholestatic diseases. The aim of this study was to elucidate gene expression profiling in the whole liver of bile duct ligated (BDL) rats using microarray analysis. In addition, the localization and time course of up-regulated expression of vascular endothelial growth factor (VEGF) was investigated.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0815-9319
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1993-2000
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pubmed:meshHeading |
pubmed-meshheading:17914982-Animals,
pubmed-meshheading:17914982-Bile Ducts,
pubmed-meshheading:17914982-Blotting, Western,
pubmed-meshheading:17914982-Cell Proliferation,
pubmed-meshheading:17914982-Cholestasis,
pubmed-meshheading:17914982-Disease Models, Animal,
pubmed-meshheading:17914982-Gene Expression Profiling,
pubmed-meshheading:17914982-Hepatocytes,
pubmed-meshheading:17914982-Immunohistochemistry,
pubmed-meshheading:17914982-Ligation,
pubmed-meshheading:17914982-Liver,
pubmed-meshheading:17914982-Male,
pubmed-meshheading:17914982-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:17914982-Portal System,
pubmed-meshheading:17914982-Rats,
pubmed-meshheading:17914982-Rats, Sprague-Dawley,
pubmed-meshheading:17914982-Time Factors,
pubmed-meshheading:17914982-Up-Regulation,
pubmed-meshheading:17914982-Vascular Endothelial Growth Factor A
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
Gene expression profiling in whole liver of bile duct ligated rats: VEGF-A expression is up-regulated in hepatocytes adjacent to the portal tracts.
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|
pubmed:affiliation |
Department of Medicine, School of Medicine, Teikyo University, Tokyo, Japan. a-tanaka@med.teikyo-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
