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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-12-31
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pubmed:abstractText |
Normal human myocardium switches substrate metabolism preference, adapting to the prevailing plasma substrate levels and hormonal milieu, but in type 1 diabetes, the myocardium relies heavily on fatty acid metabolism for energy. Whether conditions that affect myocardial glucose use and fatty acid utilization, oxidation, and storage in nondiabetic subjects alter them in type 1 diabetes is not well known.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1939-327X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
57
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
32-40
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17914030-Adult,
pubmed-meshheading:17914030-Blood Flow Velocity,
pubmed-meshheading:17914030-C-Peptide,
pubmed-meshheading:17914030-Carbon Radioisotopes,
pubmed-meshheading:17914030-Diabetes Mellitus, Type 1,
pubmed-meshheading:17914030-Echocardiography,
pubmed-meshheading:17914030-Fatty Acids, Nonesterified,
pubmed-meshheading:17914030-Female,
pubmed-meshheading:17914030-Glucose,
pubmed-meshheading:17914030-Glucose Clamp Technique,
pubmed-meshheading:17914030-Heart,
pubmed-meshheading:17914030-Humans,
pubmed-meshheading:17914030-Insulin,
pubmed-meshheading:17914030-Male,
pubmed-meshheading:17914030-Myocardium,
pubmed-meshheading:17914030-Oxygen Consumption,
pubmed-meshheading:17914030-Patient Selection,
pubmed-meshheading:17914030-Positron-Emission Tomography,
pubmed-meshheading:17914030-Reference Values
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pubmed:year |
2008
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pubmed:articleTitle |
Fatty acids and insulin modulate myocardial substrate metabolism in humans with type 1 diabetes.
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pubmed:affiliation |
Cardiovascular Division, Department of Internal Medicine, Mallinckrodt Institute, Washington University School of Medicine, St. Louis, Missouri, USA. lpeterso@im.wustl.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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