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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
5
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pubmed:dateCreated |
2007-10-4
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pubmed:abstractText |
We report a new case of transient myeloproliferative disorder (TMD) in a non Down syndrome neonate. The cytogenetic and molecular studies within from the blood blast cells identified a trisomy 21 and a partial deletion in exon 2 of the transcription factor GATA1. Spontaneous regression of the TMD was achieved at the age of 1 month as the clonal and molecular abnormalities. A survey by periodic cytological examinations of peripheral blood cells and GATA1 mutation analysis was instituted since three years and has not detected up to date acute leukaemia.
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pubmed:language |
fre
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
0003-3898
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
65
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
569-73
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pubmed:meshHeading |
pubmed-meshheading:17913678-Diseases in Twins,
pubmed-meshheading:17913678-Down Syndrome,
pubmed-meshheading:17913678-Exons,
pubmed-meshheading:17913678-Follow-Up Studies,
pubmed-meshheading:17913678-GATA1 Transcription Factor,
pubmed-meshheading:17913678-Gene Deletion,
pubmed-meshheading:17913678-Humans,
pubmed-meshheading:17913678-Infant, Newborn,
pubmed-meshheading:17913678-Infant, Premature,
pubmed-meshheading:17913678-Infant, Premature, Diseases,
pubmed-meshheading:17913678-Male,
pubmed-meshheading:17913678-Mutation,
pubmed-meshheading:17913678-Myeloproliferative Disorders,
pubmed-meshheading:17913678-Remission, Spontaneous,
pubmed-meshheading:17913678-Twins, Dizygotic
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pubmed:articleTitle |
[Transient myeloproliferative disorder in a neonate without Down syndrome].
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pubmed:affiliation |
AP-HP, Services d'hématologie biologique et clinique, Hôpital d'enfants Armand Trousseau, Paris.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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