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rdf:type |
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lifeskim:mentions |
umls-concept:C0023185,
umls-concept:C0025265,
umls-concept:C0038803,
umls-concept:C0058698,
umls-concept:C0205178,
umls-concept:C0441889,
umls-concept:C0684336,
umls-concept:C0805586,
umls-concept:C1708335,
umls-concept:C2598156,
umls-concept:C2827063
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pubmed:issue |
1
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pubmed:dateCreated |
2008-1-14
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pubmed:abstractText |
In humans, the effects of dopaminergic agents administered systemically are less clear-cut than studies in experimental animals where agents can be applied locally in the brain. DA receptor occupancy could clearly contribute to the variance in findings, although this is typically not known.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0033-3158
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
196
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
157-65
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pubmed:meshHeading |
pubmed-meshheading:17912501-Adult,
pubmed-meshheading:17912501-Affect,
pubmed-meshheading:17912501-Antipsychotic Agents,
pubmed-meshheading:17912501-Carbon Radioisotopes,
pubmed-meshheading:17912501-Corpus Striatum,
pubmed-meshheading:17912501-Dopamine Antagonists,
pubmed-meshheading:17912501-Dose-Response Relationship, Drug,
pubmed-meshheading:17912501-Double-Blind Method,
pubmed-meshheading:17912501-Humans,
pubmed-meshheading:17912501-Male,
pubmed-meshheading:17912501-Memory, Short-Term,
pubmed-meshheading:17912501-Motor Activity,
pubmed-meshheading:17912501-Neuropsychological Tests,
pubmed-meshheading:17912501-Orientation,
pubmed-meshheading:17912501-Pain Measurement,
pubmed-meshheading:17912501-Pattern Recognition, Visual,
pubmed-meshheading:17912501-Positron-Emission Tomography,
pubmed-meshheading:17912501-Probability Learning,
pubmed-meshheading:17912501-Prolactin,
pubmed-meshheading:17912501-Raclopride,
pubmed-meshheading:17912501-Reaction Time,
pubmed-meshheading:17912501-Receptors, Dopamine D2,
pubmed-meshheading:17912501-Serial Learning,
pubmed-meshheading:17912501-Sulpiride
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pubmed:year |
2008
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pubmed:articleTitle |
Dopamine D2 receptor occupancy levels of acute sulpiride challenges that produce working memory and learning impairments in healthy volunteers.
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|
pubmed:affiliation |
PET Psychiatry Group, MRC Clinical Sciences Centre, Hammersmith Hospital Imperial College, London, W12 0NN, UK. mitul.mehta2@imperial.ac.uk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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