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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0017431,
umls-concept:C0024204,
umls-concept:C0086860,
umls-concept:C0205160,
umls-concept:C0220905,
umls-concept:C0332281,
umls-concept:C0376515,
umls-concept:C0853879,
umls-concept:C1274040,
umls-concept:C1516213,
umls-concept:C1882417
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|
pubmed:issue |
19
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pubmed:dateCreated |
2007-10-2
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|
pubmed:abstractText |
Expression of the antiapoptotic and antiproliferative protein Bcl-2 has been repeatedly shown to be associated with better clinical outcome in breast cancer. We recently showed a novel regulatory (-938C>A) single-nucleotide polymorphism (SNP) in the inhibitory P2 BCL2 gene promoter generating significantly different BCL2 promoter activities.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1078-0432
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
13
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5790-7
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pubmed:meshHeading |
pubmed-meshheading:17908970-Adult,
pubmed-meshheading:17908970-Aged,
pubmed-meshheading:17908970-Female,
pubmed-meshheading:17908970-Genotype,
pubmed-meshheading:17908970-Humans,
pubmed-meshheading:17908970-Lymph Nodes,
pubmed-meshheading:17908970-Lymphatic Metastasis,
pubmed-meshheading:17908970-Middle Aged,
pubmed-meshheading:17908970-Neoplasm Invasiveness,
pubmed-meshheading:17908970-Polymorphism, Genetic,
pubmed-meshheading:17908970-Polymorphism, Single Nucleotide,
pubmed-meshheading:17908970-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:17908970-Risk,
pubmed-meshheading:17908970-Time Factors,
pubmed-meshheading:17908970-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
The AA genotype of the regulatory BCL2 promoter polymorphism ( 938C>A) is associated with a favorable outcome in lymph node negative invasive breast cancer patients.
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pubmed:affiliation |
Institute of Pharmacogenetics, University of Duisburg-Essen, Germany. hagen.bachmann@uk-essen.de
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pubmed:publicationType |
Journal Article
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