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pubmed-article:17898992pubmed:abstractTextMitogenic activity of insulin and insulin analogues and the involvement of the IGF-1 receptor (IGF-1R) is still a controversial issue. We compared levels of the proteins IGF-1R and insulin receptor (InsR) in fibroblasts and smooth muscle cells from healthy donors and assessed the downstream signalling and growth-promoting activity of insulin and insulin analogues.lld:pubmed
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pubmed-article:17898992pubmed:articleTitleIGF-1 receptor signalling determines the mitogenic potency of insulin analogues in human smooth muscle cells and fibroblasts.lld:pubmed
pubmed-article:17898992pubmed:affiliationInstitute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Auf'm Hennekamp 65, D-40225, Dusseldorf, Germany.lld:pubmed
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