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pubmed-article:17898404pubmed:abstractTextWe evaluated the epidural administration of tezampanel, a non-N-methyl-d-aspartate receptor antagonist, in a rat model for postoperative pain. We sought to determine if this drug affects nociception when administered epidurally by testing its effects on responses to heat in normal rats. The effects of epidural tezampanel on pain-related behaviors in rats that underwent plantar incision were also studied.lld:pubmed
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pubmed-article:17898404pubmed:authorpubmed-author:BrennanTimoth...lld:pubmed
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pubmed-article:17898404pubmed:pagination1152-9, table of contentslld:pubmed
pubmed-article:17898404pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:17898404pubmed:articleTitleEpidural tezampanel, an AMPA/kainate receptor antagonist, produces postoperative analgesia in rats.lld:pubmed
pubmed-article:17898404pubmed:affiliationDepartment of Anesthesia, University of Iowa College of Medicine, Iowa City, IA 52242-1079, USA. tim-brennan@uiowa.edulld:pubmed
pubmed-article:17898404pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17898404pubmed:publicationTypeResearch Support, N.I.H., Extramurallld:pubmed
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