17895832

Source:http://linkedlifedata.com/resource/pubmed/id/17895832

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0026336, umls-concept:C0026339, umls-concept:C0036667, umls-concept:C0037083, umls-concept:C0045093, umls-concept:C0086168, umls-concept:C0164786, umls-concept:C0312418, umls-concept:C1335302, umls-concept:C1710082
pubmed:issue	3
pubmed:dateCreated	2007-9-26
pubmed:abstractText	To understand the impact of protein kinase B (PKB; Akt) signaling on growth and protection from apoptosis in pancreatic ductal adenocarcinoma models demonstrating differences in PKB activity.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8608542
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/AKT1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/AKT2 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/AKT3 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Androstadienes, http://linkedlifedata.com/resource/pubmed/chemical/Antimetabolites, Antineoplastic, http://linkedlifedata.com/resource/pubmed/chemical/Deoxycytidine, http://linkedlifedata.com/resource/pubmed/chemical/Neoplasm Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylinositol 3-Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-akt, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering, http://linkedlifedata.com/resource/pubmed/chemical/gemcitabine, http://linkedlifedata.com/resource/pubmed/chemical/wortmannin
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1536-4828
pubmed:author	pubmed-author:CaoPinjiangP, pubmed-author:HedleyDavid WilliamDW, pubmed-author:PhamNhu-AnNA, pubmed-author:TsaoMing-SoundMS
pubmed:issnType	Electronic
pubmed:volume	35
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	e16-26
pubmed:dateRevised	2010-11-18
pubmed:meshHeading	pubmed-meshheading:17895832-Androstadienes, pubmed-meshheading:17895832-Animals, pubmed-meshheading:17895832-Antimetabolites, Antineoplastic, pubmed-meshheading:17895832-Apoptosis, pubmed-meshheading:17895832-Carcinoma, Pancreatic Ductal, pubmed-meshheading:17895832-Cell Hypoxia, pubmed-meshheading:17895832-Cell Line, Tumor, pubmed-meshheading:17895832-Deoxycytidine, pubmed-meshheading:17895832-Drug Resistance, Neoplasm, pubmed-meshheading:17895832-Gene Expression Profiling, pubmed-meshheading:17895832-Humans, pubmed-meshheading:17895832-Male, pubmed-meshheading:17895832-Mice, pubmed-meshheading:17895832-Mice, SCID, pubmed-meshheading:17895832-Neoplasm Proteins, pubmed-meshheading:17895832-Pancreatic Neoplasms, pubmed-meshheading:17895832-Phosphatidylinositol 3-Kinases, pubmed-meshheading:17895832-Proto-Oncogene Proteins c-akt, pubmed-meshheading:17895832-RNA, Small Interfering, pubmed-meshheading:17895832-Signal Transduction, pubmed-meshheading:17895832-Xenograft Model Antitumor Assays
pubmed:year	2007
pubmed:articleTitle	Dissociation of gemcitabine sensitivity and protein kinase B signaling in pancreatic ductal adenocarcinoma models.
pubmed:affiliation	Ontario Cancer Institute and Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't