Linked Life Data

17895503

Source:http://linkedlifedata.com/resource/pubmed/id/17895503

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2008-1-9
pubmed:abstractText
Thrombomodulin is a critical cofactor in the initiation of the protein C anticoagulant pathway. Plasma levels of thrombomodulin are regulated on a genetic basis, but more important is the dependence on a series of other atherosclerotic risk factors, such as hypertriglyceridemia, stroke, cancer, and diabetes. There is considerable controversy regarding the clinical role of thrombomodulin level as a risk factor of severe preeclampsia. A retrospective analysis of recent reports on the thrombomodulin level and its correlation to preeclampsia was performed to assess the correlation between the pattern of thrombomodulin level and preeclampsia. From the available 4 case-control studies, 149 patients and 120 controls are evaluated. The overall average thrombomodulin level for the patients and controls is 66.7+/-11.9 ng/mL and 45.7+/-7.3 ng/mL, respectively, which is significantly higher in patients than in controls (P< .05). In addition, the author reports a significant correlation between population ethnicity and thrombomodulin level (r= .96; P< .05).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1076-0296
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-101
pubmed:meshHeading
pubmed:year
2008
pubmed:articleTitle
Correlation between thrombomodulin and severe preeclampsia: a summary.
pubmed:affiliation
Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. wviroj@yahoo.com
pubmed:publicationType
Journal Article