Linked Life Data

17891664

Source:http://linkedlifedata.com/resource/pubmed/id/17891664

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-9-24
pubmed:abstractText
An assay in which groups perform at both similar and significantly different levels within the same test session may have experimental advantages both in understanding underlying behavioral-cognitive processes and in helping to resolve neuroimaging issues regarding functional significance vs. performance confounds. Here we report behavioral data from a response inhibition (Go/No-Go) task with two levels of No-Go difficulty (easy, hard). The sample included individuals with current cocaine dependence (N=18) and controls (N=15). Using signal detection methodology (d' and Beta), significant main effects were observed for group and trial type on d'. Post-hoc analyses revealed the cocaine-dependent individuals performed significantly worse than controls on difficult, but not easy, trials. Differences on d' but not Beta, and slower reaction times in cocaine subjects, suggest that response inhibition deficits were related to disruption in visual information processing rather than inhibition of motor activity.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0095-2990
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
717-26
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:17891664-Adult, pubmed-meshheading:17891664-Attention, pubmed-meshheading:17891664-Cocaine-Related Disorders, pubmed-meshheading:17891664-Control Groups, pubmed-meshheading:17891664-Diagnosis, Computer-Assisted, pubmed-meshheading:17891664-Diagnostic and Statistical Manual of Mental Disorders, pubmed-meshheading:17891664-Female, pubmed-meshheading:17891664-Humans, pubmed-meshheading:17891664-Impulsive Behavior, pubmed-meshheading:17891664-Inhibition (Psychology), pubmed-meshheading:17891664-Male, pubmed-meshheading:17891664-Middle Aged, pubmed-meshheading:17891664-Psychiatric Status Rating Scales, pubmed-meshheading:17891664-Psychomotor Performance, pubmed-meshheading:17891664-Reaction Time, pubmed-meshheading:17891664-Signal Detection, Psychological, pubmed-meshheading:17891664-Visual Perception
pubmed:year
2007
pubmed:articleTitle
Performance of cocaine dependent individuals and controls on a response inhibition task with varying levels of difficulty.
pubmed:affiliation
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, Texas 77030, USA. scott.d.lane@uth.tmc.edu
pubmed:publicationType
Journal Article, Research Support, N.I.H., Extramural