17891166

Source:http://linkedlifedata.com/resource/pubmed/id/17891166

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0011853, umls-concept:C0087111, umls-concept:C0205178, umls-concept:C0205191, umls-concept:C0529793, umls-concept:C0542341, umls-concept:C1801960, umls-concept:C2923059
pubmed:issue	5
pubmed:dateCreated	2008-3-3
pubmed:abstractText	Diabetes-associated vascular dysfunction contributes to increased cardiovascular risk. We investigated whether the phosphodiesterase-5 inhibitor sildenafil would improve vascular function in diabetic rats.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7502536
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine, http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase, http://linkedlifedata.com/resource/pubmed/chemical/Phosphodiesterase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Piperazines, http://linkedlifedata.com/resource/pubmed/chemical/Purines, http://linkedlifedata.com/resource/pubmed/chemical/Streptozocin, http://linkedlifedata.com/resource/pubmed/chemical/Sulfones, http://linkedlifedata.com/resource/pubmed/chemical/Superoxides, http://linkedlifedata.com/resource/pubmed/chemical/sildenafil
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0007-1188
pubmed:author	pubmed-author:BauersachsJJ, pubmed-author:EigenthalerMM, pubmed-author:ErtlGG, pubmed-author:FlierlUU, pubmed-author:FraccarolloDD, pubmed-author:KobsarAA, pubmed-author:PförtschSS, pubmed-author:PfrangJJ, pubmed-author:RennéTT, pubmed-author:SchäferAA, pubmed-author:VogtCC
pubmed:issnType	Print
pubmed:volume	153
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	886-93
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:17891166-Acetylcholine, pubmed-meshheading:17891166-Animals, pubmed-meshheading:17891166-Aorta, Thoracic, pubmed-meshheading:17891166-Diabetes Mellitus, Experimental, pubmed-meshheading:17891166-Dose-Response Relationship, Drug, pubmed-meshheading:17891166-Drug Administration Schedule, pubmed-meshheading:17891166-Endothelium, Vascular, pubmed-meshheading:17891166-Male, pubmed-meshheading:17891166-Nitric Oxide Synthase, pubmed-meshheading:17891166-Oxidative Stress, pubmed-meshheading:17891166-Phosphodiesterase Inhibitors, pubmed-meshheading:17891166-Piperazines, pubmed-meshheading:17891166-Purines, pubmed-meshheading:17891166-Rats, pubmed-meshheading:17891166-Rats, Wistar, pubmed-meshheading:17891166-Streptozocin, pubmed-meshheading:17891166-Sulfones, pubmed-meshheading:17891166-Superoxides, pubmed-meshheading:17891166-Vasodilation
pubmed:year	2008
pubmed:articleTitle	Improvement of vascular function by acute and chronic treatment with the PDE-5 inhibitor sildenafil in experimental diabetes mellitus.
pubmed:affiliation	Medizinische Klinik und Poliklinik I, Universitätsklinikum Würzburg, Julius-Maximilians-Universität Würzburg, Würzburg, Bavaria, Germany. a.schaefer@medizin.uni-wuerzburg.de
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't