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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-9-24
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pubmed:abstractText |
A series of 92 Chinese children newly diagnosed with acute lymphoblastic leukemia (ALL) were examined for the ETV6-RUNX1 (previously TEL-AML1) fusion gene by using a nested reverse transcriptase-polymerase chain reaction. ETV6-RUNX1 fusion transcripts were detected in 21 of 92 patients (22.8%): 16 with common ALL, 4 with precursor B-cell ALL, and 1 with T-ALL. The prevalence of ETV6-RUNX1 positivity was 24.7% (20/81) in childhood B-lineage ALL. The prevalence of ETV6-RUNX1 in Chinese pediatric ALL patients proved to be similar to that found in other countries.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0165-4608
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
178
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-60
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:17889709-Child,
pubmed-meshheading:17889709-Child, Preschool,
pubmed-meshheading:17889709-China,
pubmed-meshheading:17889709-Core Binding Factor Alpha 2 Subunit,
pubmed-meshheading:17889709-Female,
pubmed-meshheading:17889709-Gene Rearrangement,
pubmed-meshheading:17889709-Humans,
pubmed-meshheading:17889709-Immunophenotyping,
pubmed-meshheading:17889709-Infant,
pubmed-meshheading:17889709-Infant, Newborn,
pubmed-meshheading:17889709-Male,
pubmed-meshheading:17889709-Models, Genetic,
pubmed-meshheading:17889709-Oncogene Proteins, Fusion,
pubmed-meshheading:17889709-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:17889709-Proto-Oncogene Proteins c-ets,
pubmed-meshheading:17889709-Repressor Proteins,
pubmed-meshheading:17889709-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2007
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pubmed:articleTitle |
Prevalence of ETV6-RUNX1 fusion gene in children with acute lymphoblastic leukemia in China.
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pubmed:affiliation |
Division of Hematology/Oncology, Children's Hospital Fudan University, 183 Fenglin Road, Shanghai 200032, China. gaoyijin@hotmail.com
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pubmed:publicationType |
Journal Article
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