Linked Life Data

17883282

Source:http://linkedlifedata.com/resource/pubmed/id/17883282

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
14
pubmed:dateCreated
2007-9-21
pubmed:abstractText
Durable and sustained suppression of HIV replication can be achieved as demonstrated in several recent clinical trials of antiretroviral (ARV) regimens. However, the efficacy demonstrated in the experimental setting does not always translate to effectiveness in the clinical setting. The frequency and number of medications (conventionally referred to as the pill count) contribute to regimen effectiveness. However, clinicians and HIV-infected patients recognise that there are several other characteristics of an ARV regimen that are equally important contributors to its effectiveness. Potency and durability, the potential for drug-drug interactions, and the occurrence of adverse events also contribute to the effectiveness and complexity of a drug regimen. A comprehensive consideration of factors associated with efficacy will optimise the translation to effectiveness for the individual infected with HIV.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0012-6667
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1969-79
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Translating efficacy into effectiveness in antiretroviral therapy: beyond the pill count.
pubmed:affiliation
Clinical Pharmacy and Infectious Diseases, University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA. courtney.fletcher@UCHSC.EDU
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't