rdf:type |
|
lifeskim:mentions |
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0026820,
umls-concept:C0034693,
umls-concept:C0132555,
umls-concept:C0205276,
umls-concept:C0229666,
umls-concept:C0232338,
umls-concept:C0242692,
umls-concept:C0392756,
umls-concept:C0444498,
umls-concept:C0599781
|
pubmed:issue |
12
|
pubmed:dateCreated |
2007-11-28
|
pubmed:abstractText |
We have previously shown in humans that local infusion of a nitric oxide synthase (NOS) inhibitor into the femoral artery attenuates the increase in leg glucose uptake during exercise without influencing total leg blood flow. However, rodent studies examining the effect of NOS inhibition on contraction-stimulated skeletal muscle glucose uptake have yielded contradictory results. This study examined the effect of local infusion of an NOS inhibitor on skeletal muscle glucose uptake (2-deoxyglucose) and capillary blood flow (contrast-enhanced ultrasound) during in situ contractions in rats.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
1939-327X
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
56
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2885-92
|
pubmed:meshHeading |
pubmed-meshheading:17881613-Animals,
pubmed-meshheading:17881613-Blood Flow Velocity,
pubmed-meshheading:17881613-Capillaries,
pubmed-meshheading:17881613-Enzyme Inhibitors,
pubmed-meshheading:17881613-Glucose,
pubmed-meshheading:17881613-Male,
pubmed-meshheading:17881613-Muscle, Skeletal,
pubmed-meshheading:17881613-Muscle Contraction,
pubmed-meshheading:17881613-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:17881613-Nitric Oxide,
pubmed-meshheading:17881613-Nitric Oxide Synthase Type III,
pubmed-meshheading:17881613-Rats,
pubmed-meshheading:17881613-Rats, Wistar
|
pubmed:year |
2007
|
pubmed:articleTitle |
Local nitric oxide synthase inhibition reduces skeletal muscle glucose uptake but not capillary blood flow during in situ muscle contraction in rats.
|
pubmed:affiliation |
Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|