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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1992-3-24
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pubmed:abstractText |
The yawns and penile erection elicited in rats by apomorphine (100 micrograms/kg SC) are dose-dependently suppressed by the enkephalinase-resistant analog of NT, [D-Trp11]NT, intracerebroventricularly (ICV) injected (10-120 ng per rat). This antagonistic effect was shared by NT (0.75-3 micrograms per rat) administered ICV. The yawns induced by pilocarpine (2 mg/kg IP) were similarly antagonized by [D-Trp11]NT (30-120 ng per rat). The enkephalinase inhibitor acetorphan (5 mg/kg IV) reduced in a naloxone (2 mg/kg, SC)-resistant manner the apomorphine-induced penile erection or yawning.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0196-9781
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
755-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1788138-Animals,
pubmed-meshheading:1788138-Apomorphine,
pubmed-meshheading:1788138-Drug Antagonism,
pubmed-meshheading:1788138-Male,
pubmed-meshheading:1788138-Naloxone,
pubmed-meshheading:1788138-Neprilysin,
pubmed-meshheading:1788138-Neurotensin,
pubmed-meshheading:1788138-Penile Erection,
pubmed-meshheading:1788138-Rats,
pubmed-meshheading:1788138-Rats, Inbred Strains,
pubmed-meshheading:1788138-Thiorphan,
pubmed-meshheading:1788138-Yawning
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pubmed:articleTitle |
Inhibition of apomorphine-induced yawning and penile erection by neurotensin.
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pubmed:affiliation |
European Institute for Peptide Research, Unité de Neuropsychopharmacologie Expérimentale U.R.A. 1170 du C.N.R.S., Faculté de Médecine et Pharmacie de Rouen, Saint Etienne Du Rouvray, France.
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pubmed:publicationType |
Journal Article
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