Linked Life Data

17875590

Source:http://linkedlifedata.com/resource/pubmed/id/17875590

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
958
pubmed:dateCreated
2007-10-25
pubmed:abstractText
The aim of this study was to evaluate the anatomical and clinical relationship between lacunar infarction and the corticospinal tract (CST) in patients with acute lacunar infarction and predict clinical outcome. We examined 28 pyramidal tract stroke patients in the acute phase or early subacute phase (<3 days) with a marked motor deficit. The anatomical location and the extent of CST involvement within the infarcts were visualized on three-dimensional colour-coded diffusion tensor tractography (DTT). With regard to the CST, all patients were divided into three clinical subgroups: Group 1 (intact type), Group 2 (partial involvement type) and Group 3 (whole involvement type). Subsequently, the severity of the motor deficit of each patient was determined according to the National Institutes of Health Stroke Scale (NIHSS) scores at the acute/early subacute phase (<3 days after onset of symptoms), early chronic phase (8-14 days) and outcome (30-60 days). NIHSS scores of Group 1 (12/28) were significantly lower than those of Group 2 (9/28) at the acute phase or early subacute phase (U = -2.816, p<0.01), and those of Group 2 were significantly lower than those of Group 3 (7/28) (U = -3.136, p<0.01). At outcome,NIHSS scores of Group 1 were significantly lower than those of Group 2 (U = -2.846, p<0.01), and scores of Group 2 were significantly lower than those of Group 3 (U = -3.130, p<0.01). At the same time, the NIHSS scores of each group gradually decreased from acute phase to outcome, Neurological improvement was statistically different among the three topographical types of infarction (H = 26.15, p<0.01; H = 11.03, p<0.01; H = 10.05, p<0.01). In conclusion, the three-dimensional colour-coded DTT allows in vivo differentiation of distinct CST stroke subtypes and may help in better establishing the prognosis for patients after CST stroke.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1748-880X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
782-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
White matter tractography by diffusion tensor imaging plays an important role in prognosis estimation of acute lacunar infarctions.
pubmed:affiliation
Department of Radiology, The Children's Hospital, The Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. laican1@126.com
pubmed:publicationType
Journal Article