rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2007-10-2
|
pubmed:abstractText |
6-(18)F-fluoro-l-3,4-dihydroxyphenylalanine ((18)F-DOPA) PET is a useful tool for the detection of certain neuroendocrine tumors, especially with the preadministration of carbidopa, an inhibitor of DOPA decarboxylase. Whether carbidopa also improves (18)F-DOPA PET of adrenal pheochromocytomas and extraadrenal paragangliomas is unknown. The aim of this study was to investigate the sensitivity of (18)F-DOPA PET in the detection of paraganglioma and its metastatic lesions and to evaluate whether tracer uptake by the tumors is enhanced by carbidopa.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0161-5505
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
48
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1599-606
|
pubmed:meshHeading |
pubmed-meshheading:17873132-Abdominal Neoplasms,
pubmed-meshheading:17873132-Adrenal Gland Neoplasms,
pubmed-meshheading:17873132-Carbidopa,
pubmed-meshheading:17873132-Dihydroxyphenylalanine,
pubmed-meshheading:17873132-Female,
pubmed-meshheading:17873132-Humans,
pubmed-meshheading:17873132-Image Enhancement,
pubmed-meshheading:17873132-Male,
pubmed-meshheading:17873132-Metabolic Clearance Rate,
pubmed-meshheading:17873132-Middle Aged,
pubmed-meshheading:17873132-Paraganglioma, Extra-Adrenal,
pubmed-meshheading:17873132-Pheochromocytoma,
pubmed-meshheading:17873132-Positron-Emission Tomography,
pubmed-meshheading:17873132-Radiopharmaceuticals
|
pubmed:year |
2007
|
pubmed:articleTitle |
The effects of carbidopa on uptake of 6-18F-Fluoro-L-DOPA in PET of pheochromocytoma and extraadrenal abdominal paraganglioma.
|
pubmed:affiliation |
Reproductive Biology and Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-1109, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, N.I.H., Intramural
|