|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2007-10-18
|
|
pubmed:abstractText |
4-Hydroxy-2-nonenal (4-HNE) is an abundant electrophilic lipid that mediates oxidative stress in endothelium by mechanisms that remain controversial. This study examines the effects of 4-HNE on nitric oxide (NO) and superoxide levels in bovine aorta endothelial cells (BAECs).
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/4-hydroxy-2-nonenal,
http://linkedlifedata.com/resource/pubmed/chemical/5,6,7,8-tetrahydrobiopterin,
http://linkedlifedata.com/resource/pubmed/chemical/Aldehydes,
http://linkedlifedata.com/resource/pubmed/chemical/Biopterin,
http://linkedlifedata.com/resource/pubmed/chemical/GTP Cyclohydrolase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type III,
http://linkedlifedata.com/resource/pubmed/chemical/Proteasome Endopeptidase Complex,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
1524-4636
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
27
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2340-7
|
|
pubmed:dateRevised |
2007-12-3
|
|
pubmed:meshHeading |
pubmed-meshheading:17872449-Aldehydes,
pubmed-meshheading:17872449-Animals,
pubmed-meshheading:17872449-Aorta,
pubmed-meshheading:17872449-Biopterin,
pubmed-meshheading:17872449-Cattle,
pubmed-meshheading:17872449-Cells, Cultured,
pubmed-meshheading:17872449-Endothelial Cells,
pubmed-meshheading:17872449-GTP Cyclohydrolase,
pubmed-meshheading:17872449-Nitric Oxide,
pubmed-meshheading:17872449-Nitric Oxide Synthase Type III,
pubmed-meshheading:17872449-Proteasome Endopeptidase Complex,
pubmed-meshheading:17872449-Superoxides
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
4-Hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation.
|
|
pubmed:affiliation |
Department of Biophysics, Medical College of Wisconsin, Milwaukee, USA.
|
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|
