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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2007-11-23
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pubmed:abstractText |
Heparins and warfarin are currently used as venous thromboembolism (VTE) prophylaxis in surgery. Inhibition of factor (F) Xa provides a specific mechanism of anticoagulation and the potential for an improved benefit-risk profile.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1538-7933
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2368-75
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pubmed:meshHeading |
pubmed-meshheading:17868430-Administration, Oral,
pubmed-meshheading:17868430-Adult,
pubmed-meshheading:17868430-Aged,
pubmed-meshheading:17868430-Aged, 80 and over,
pubmed-meshheading:17868430-Argentina,
pubmed-meshheading:17868430-Arthroplasty, Replacement, Knee,
pubmed-meshheading:17868430-Dose-Response Relationship, Drug,
pubmed-meshheading:17868430-Drug Administration Schedule,
pubmed-meshheading:17868430-Enoxaparin,
pubmed-meshheading:17868430-Europe,
pubmed-meshheading:17868430-Factor Xa,
pubmed-meshheading:17868430-Female,
pubmed-meshheading:17868430-Fibrinolytic Agents,
pubmed-meshheading:17868430-Hemorrhage,
pubmed-meshheading:17868430-Humans,
pubmed-meshheading:17868430-Israel,
pubmed-meshheading:17868430-Male,
pubmed-meshheading:17868430-Middle Aged,
pubmed-meshheading:17868430-North America,
pubmed-meshheading:17868430-Pyrazoles,
pubmed-meshheading:17868430-Pyridones,
pubmed-meshheading:17868430-Risk Assessment,
pubmed-meshheading:17868430-South Australia,
pubmed-meshheading:17868430-Treatment Outcome,
pubmed-meshheading:17868430-Venous Thromboembolism,
pubmed-meshheading:17868430-Warfarin
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pubmed:year |
2007
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pubmed:articleTitle |
The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement.
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pubmed:affiliation |
Department of Orthopaedics and Clinical Trial Unit, Nordsjaellands Hospital Hoersholm, University of Copenhagen, Usseroed Kongevej 102, Hoersholm, Denmark. mirula@noh.regionh.dk
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Multicenter Study,
Clinical Trial, Phase II
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