Linked Life Data

1785707

Source:http://linkedlifedata.com/resource/pubmed/id/1785707

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-3-16
pubmed:abstractText
A study was designed to assess the possible effects of intravenous clonidine on postoperative shivering. Fifty patients undergoing spinal fusion under isoflurane anaesthesia were randomly assigned to two groups (n = 25). Patients in one group were given intravenous clonidine (5 micrograms.kg-1 during the first hour, and 0.3 microgram.kg-1.h-1 thereafter) or placebo. Shivering intensity (rated from 0 to 2) and pulmonary artery blood temperature (theta) was recorded every ten minutes for two hours. Haemodynamic and metabolic data were obtained by way of a Swan-Ganz catheter prior to administering the test drug, and then after 1 and 2 hours. On arrival at the recovery room, theta was 36.2 +/- 0.3 degrees C in the clonidine group, and 36.5 +/- 0.2 degrees C in the placebo group. There were no significant differences in shivering between the two groups. Clonidine significantly decreased blood pressure, heart rate, cardiac output and whole body oxygen consumption. The patients in these series were free from any cardiac disease. Further studies are required to assess the possible beneficial effects of clonidine on postoperative oxygen consumption in patients suffering from heart failure.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0750-7658
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
554-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Effects of intravenous clonidine on postoperative shivering].
pubmed:affiliation
Département d'Anesthésie-Réanimation, Hôtel-Dieu, Nantes.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract, Randomized Controlled Trial