Source:http://linkedlifedata.com/resource/pubmed/id/17855149
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2008-6-2
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pubmed:abstractText |
[(11)C]-PIB positron emission tomography ([(11)C]-PIB PET) is a sensitive marker of amyloid in Alzheimer's disease (AD), but its specificity has not been fully evaluated. Vascular amyloid-beta deposition is common in Parkinson's disease (PD) and alpha-synuclein, the major component of the Lewy bodies in PD, forms amyloid fibrils. We investigated five apparently cognitively normal PD patients with [(11)C]-PIB PET. The results were compared to 16 patients with AD and six healthy controls from a previous study. [(11)C]-PIB retention was not significantly increased in our patients who all had early stage PD. Further studies of more advanced PD patients are warranted.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1353-8020
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
345-7
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pubmed:meshHeading |
pubmed-meshheading:17855149-Aged,
pubmed-meshheading:17855149-Benzothiazoles,
pubmed-meshheading:17855149-Brain Mapping,
pubmed-meshheading:17855149-Female,
pubmed-meshheading:17855149-Humans,
pubmed-meshheading:17855149-Image Processing, Computer-Assisted,
pubmed-meshheading:17855149-Male,
pubmed-meshheading:17855149-Middle Aged,
pubmed-meshheading:17855149-Parkinson Disease,
pubmed-meshheading:17855149-Positron-Emission Tomography
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pubmed:year |
2008
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pubmed:articleTitle |
[(11)C]-PIB imaging in patients with Parkinson's disease: preliminary results.
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pubmed:affiliation |
Department of Neurology, University Hospital, SE-751 85 Uppsala, Sweden. anders.johansson@neurologi.uu.se
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
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